Omnira

LABORATORY NOTEBOOK · v1

VOLUME 01 · APTAMERS

Rational aptamer

discovery,

kept on paper.

A bound, page-by-page workspace for in silico screening, hotspot consensus and directed evolution — built around Boltz-2 structural prediction.

01.

Generate a pool

Random or templated 30-nt single strands.

02.

Screen with Boltz-2

Structural docking via NVIDIA's API.

03.

Find your hotspots

Per-residue contact consensus across runs.

04.

Evolve, on paper

PSSM-guided directed evolution rounds.

PUBLISHED BY

OMNIRA RESEARCH

ENGINE

NVIDIA · BOLTZ-2

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